Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads

Immunotherapies are a promising advance in cancer treatment. However, because only a subset of cancer patients benefits from these treatments it is important to find mechanisms that will broaden the responding patient population. Generally, tumors with high mutational burdens have the potential to e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Lussier, Danielle M., Alspach, Elise, Ward, Jeffrey P., Miceli, Alexander P., Runci, Daniele, White, J. Michael, Mpoy, Cedric, Arthur, Cora D., Kohlmiller, Heather N., Jacks, Tyler, Artyomov, Maxim N., Rogers, Buck E., Schreiber, Robert D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2021
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214694/
https://ncbi.nlm.nih.gov/pubmed/34099555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2102611118
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