MHC-II neoantigens shape tumor immunity and response to immunotherapy

The ability of the immune system to eliminate and shape the immunogenicity of tumors defines the process of cancer immunoediting(1). Immunotherapies such as those that target immune checkpoint molecules can be used to augment immune-mediated elimination of tumors and have resulted in durable respons...

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Publicat a:Nature
Autors principals: Alspach, Elise, Lussier, Danielle M., Miceli, Alexander P., Kizhvatov, Ilya, DuPage, Michel, Luoma, Adrienne M., Meng, Wei, Lichti, Cheryl F., Esaulova, Ekaterina, Vomund, Anthony N., Runci, Daniele, Ward, Jeffrey P., Gubin, Matthew M., Medrano, Ruan F.V., Arthur, Cora D., White, J. Michael, Sheehan, Kathleen C.F., Chen, Alex, Wucherpfennig, Kai W., Jacks, Tyler, Unanue, Emil R., Artyomov, Maxim N., Schreiber, Robert D.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858572/
https://ncbi.nlm.nih.gov/pubmed/31645760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1671-8
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