MHC-II neoantigens shape tumor immunity and response to immunotherapy

The ability of the immune system to eliminate and shape the immunogenicity of tumors defines the process of cancer immunoediting(1). Immunotherapies such as those that target immune checkpoint molecules can be used to augment immune-mediated elimination of tumors and have resulted in durable respons...

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Publicado en:Nature
Autores principales: Alspach, Elise, Lussier, Danielle M., Miceli, Alexander P., Kizhvatov, Ilya, DuPage, Michel, Luoma, Adrienne M., Meng, Wei, Lichti, Cheryl F., Esaulova, Ekaterina, Vomund, Anthony N., Runci, Daniele, Ward, Jeffrey P., Gubin, Matthew M., Medrano, Ruan F.V., Arthur, Cora D., White, J. Michael, Sheehan, Kathleen C.F., Chen, Alex, Wucherpfennig, Kai W., Jacks, Tyler, Unanue, Emil R., Artyomov, Maxim N., Schreiber, Robert D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858572/
https://ncbi.nlm.nih.gov/pubmed/31645760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1671-8
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