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The Role of Neoantigens in Naturally Occurring and Therapeutically Induced Immune Responses to Cancer

Definitive experimental evidence from mouse cancer models and strong correlative clinical data gave rise to the Cancer Immunoediting concept that explains the dual host-protective and tumor-promoting actions of immunity on developing cancers. Tumor-specific neoantigens can serve as targets of sponta...

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Detalhes bibliográficos
Publicado no:Adv Immunol
Main Authors: Ward, Jeffrey P., Gubin, Matthew M., Schreiber, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087548/
https://ncbi.nlm.nih.gov/pubmed/26922999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.ai.2016.01.001
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