Breast cancer neoantigens can induce CD8(+) T-cell responses and antitumor immunity

Next-generation sequencing technologies have provided insights into the biology and mutational landscape of cancer. Here we evaluate the relevance of cancer neoantigens in human breast cancers. Using patient-derived xenografts from three patients with advanced breast cancer (xenografts were designat...

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Publicado no:Cancer Immunol Res
Main Authors: Zhang, Xiuli, Kim, Samuel, Hundal, Jasreet, Herndon, John M., Li, Shunqiang, Petti, Allegra A., Soysal, Savas D., Li, Lijin, McLellan, Mike D., Hoog, Jeremy, Primeau, Tina, Myers, Nancy, Vickery, Tammi L., Sturmoski, Mark, Hagemann, Ian S., Miller, Chris A., Ellis, Matthew J., Mardis, Elaine R., Hansen, Ted, Fleming, Timothy P., Goedegebuure, S. Peter, Gillanders, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647648/
https://ncbi.nlm.nih.gov/pubmed/28619968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0264
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