Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma

Head and neck squamous cell carcinomas (HNSCC) are an ideal immunotherapy target due to their high mutation burden and frequent infiltration with lymphocytes. Preclinical models to investigate targeted and combination therapies as well as defining biomarkers to guide treatment represent an important...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Zolkind, Paul, Przybylski, Dariusz, Marjanovic, Nemanja, Nguyen, Lan, Lin, Tianxiang, Johanns, Tanner, Alexandrov, Anton, Zhou, Liye, Allen, Clint T., Miceli, Alexander P., Schreiber, Robert D., Artyomov, Maxim, Dunn, Gavin P., Uppaluri, Ravindra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790525/
https://ncbi.nlm.nih.gov/pubmed/29423108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23751
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