Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma

Head and neck squamous cell carcinomas (HNSCC) are an ideal immunotherapy target due to their high mutation burden and frequent infiltration with lymphocytes. Preclinical models to investigate targeted and combination therapies as well as defining biomarkers to guide treatment represent an important...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Zolkind, Paul, Przybylski, Dariusz, Marjanovic, Nemanja, Nguyen, Lan, Lin, Tianxiang, Johanns, Tanner, Alexandrov, Anton, Zhou, Liye, Allen, Clint T., Miceli, Alexander P., Schreiber, Robert D., Artyomov, Maxim, Dunn, Gavin P., Uppaluri, Ravindra
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790525/
https://ncbi.nlm.nih.gov/pubmed/29423108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23751
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