Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma

Head and neck squamous cell carcinomas (HNSCC) are an ideal immunotherapy target due to their high mutation burden and frequent infiltration with lymphocytes. Preclinical models to investigate targeted and combination therapies as well as defining biomarkers to guide treatment represent an important...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zolkind, Paul, Przybylski, Dariusz, Marjanovic, Nemanja, Nguyen, Lan, Lin, Tianxiang, Johanns, Tanner, Alexandrov, Anton, Zhou, Liye, Allen, Clint T., Miceli, Alexander P., Schreiber, Robert D., Artyomov, Maxim, Dunn, Gavin P., Uppaluri, Ravindra
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790525/
https://ncbi.nlm.nih.gov/pubmed/29423108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23751
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