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Topoisomerase II Poisons: Converting Essential Enzymes into Molecular Scissors
The extensive length, compaction, and interwound nature of DNA, together with its controlled and restricted movement in eukaryotic cells, create a number of topological issues that profoundly affect all of the functions of the genetic material. Topoisomerases are essential enzymes that modulate the...
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| Publicat a: | Biochemistry |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8209676/ https://ncbi.nlm.nih.gov/pubmed/34008964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.1c00240 |
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