STAT3-mediated effects of methyltransferase inhibitor 5-aza-2’-deoxycytidine on preeclampsia

Objective: To investigate the effects of 5-aza-2’-deoxycytidine (5-AZA-DC) on preeclampsia (PE) and functional mechanisms dependent on STAT3. Materials and methods: Trophoblastic cells (HTR8/Svneo, JEG-3, JAR and BeWo) were used to constructed STAT3-overexpressing or -silenced cells. qRT-PCR, Wester...

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Udgivet i:Am J Transl Res
Main Authors: Zhang, Xiaoli, Wang, Gang, Li, Hui, Jiang, Xiangming, Zhao, Xiaoyong
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2021
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205656/
https://ncbi.nlm.nih.gov/pubmed/34150002
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