AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine

Activation-induced cytidine deaminase (AID) was originally identified as an inducer of somatic hypermutation (SHM) and class switch recombination (CSR) in immunoglobulin genes. However, AID can also cause mutations in host genes and contribute to cancer progression and drug resistance. In this study...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Tsai, Chiou-Tsun, Yang, Pei-Ming, Chern, Ting-Rong, Chuang, Shu-Hui, Lin, Jung-Hsin, Klemm, Lars, Müschen, Markus, Chen, Ching-Chow
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2013
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960202/
https://ncbi.nlm.nih.gov/pubmed/24457556
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki