AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine

Activation-induced cytidine deaminase (AID) was originally identified as an inducer of somatic hypermutation (SHM) and class switch recombination (CSR) in immunoglobulin genes. However, AID can also cause mutations in host genes and contribute to cancer progression and drug resistance. In this study...

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Détails bibliographiques
Auteurs principaux: Tsai, Chiou-Tsun, Yang, Pei-Ming, Chern, Ting-Rong, Chuang, Shu-Hui, Lin, Jung-Hsin, Klemm, Lars, Müschen, Markus, Chen, Ching-Chow
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2013
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960202/
https://ncbi.nlm.nih.gov/pubmed/24457556
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