Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives

BACKGROUND: Teratocarcinoma is a malignant male germ cell tumour, which contains stem cells and differentiated cancer tissues. DNMT3B has been shown to be highly expressed in human teratocarcinoma stem cells, and to mediate cytotoxicity of Aza-deoxycytidine (Aza-dC) in a pluripotent stem cell line N...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Wongtrakoongate, P, Li, J, Andrews, P W
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
Assuntos:
Genetics & Genomics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992495/
https://ncbi.nlm.nih.gov/pubmed/24603304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.128
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares