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Chemometric Outlier Classification of 2D-NMR Spectra to Enable Higher Order Structure Characterization of Protein Therapeutics
Protein therapeutics are vitally important clinically and commercially, with monoclonal antibody (mAb) therapeutic sales alone accounting for $115 billion in revenue for 2018.[1] In order for these therapeutics to be safe and efficacious, their protein components must maintain their high order struc...
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| Publicado no: | Chemometr Intell Lab Syst |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204403/ https://ncbi.nlm.nih.gov/pubmed/34135539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemolab.2020.103973 |
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