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Chemometric Outlier Classification of 2D-NMR Spectra to Enable Higher Order Structure Characterization of Protein Therapeutics

Protein therapeutics are vitally important clinically and commercially, with monoclonal antibody (mAb) therapeutic sales alone accounting for $115 billion in revenue for 2018.[1] In order for these therapeutics to be safe and efficacious, their protein components must maintain their high order struc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chemometr Intell Lab Syst
Egile Nagusiak: Sheen, David A., Shen, Vincent K., Brinson, Robert G., Arbogast, Luke W., Marino, John P., Delaglio, Frank
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204403/
https://ncbi.nlm.nih.gov/pubmed/34135539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemolab.2020.103973
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