載入...
4-Phenylbutyrate (PBA) treatment reduces hyperglycemia and islet amyloid in a mouse model of type 2 diabetes and obesity
Amyloid deposits in pancreatic islets, mainly formed by human islet amyloid polypeptide (hIAPP) aggregation, have been associated with loss of β-cell mass and function, and are a pathological hallmark of type 2 diabetes (T2D). Treatment with chaperones has been associated with a decrease in endoplas...
Na minha lista:
| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2021
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178353/ https://ncbi.nlm.nih.gov/pubmed/34088954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91311-2 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|