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Exploring the evolutionary history of kinetic stability in the alpha-lytic protease family
In addition to encoding the tertiary fold and stability, the primary sequence of a protein encodes the folding trajectory and kinetic barriers that determine the speed of folding. How these kinetic barriers are encoded is not well understood. Here, we use evolutionary sequence variation in the alpha...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8174401/ https://ncbi.nlm.nih.gov/pubmed/33433210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00720 |
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