Wordt geladen...

Exploring the evolutionary history of kinetic stability in the alpha-lytic protease family

In addition to encoding the tertiary fold and stability, the primary sequence of a protein encodes the folding trajectory and kinetic barriers that determine the speed of folding. How these kinetic barriers are encoded is not well understood. Here, we use evolutionary sequence variation in the alpha...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Biochemistry
Hoofdauteurs: Nixon, Charlotte F., Lim, Shion A., Sailer, Zachary R., Zheludev, Ivan N., Gee, Christine L., Kelch, Brian A., Harms, Michael J., Marqusee, Susan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174401/
https://ncbi.nlm.nih.gov/pubmed/33433210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00720
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!