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The burst-phase folding intermediate of ribonuclease H changes conformation over evolutionary history
The amino acid sequence encodes the energy landscape of a protein. Therefore, we expect evolutionary mutations to change features of the protein energy landscape, including the conformations adopted by a polypeptide as it folds to its native state. Ribonucleases H (RNase H) from E. coli and T. therm...
Gorde:
| Argitaratua izan da: | Biopolymers |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6047922/ https://ncbi.nlm.nih.gov/pubmed/29152711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.23086 |
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