IGF1-Stimulated Posttraumatic Hippocampal Remodeling Is Not Dependent on mTOR

Adult hippocampal neurogenesis is stimulated acutely following traumatic brain injury (TBI). However, many hippocampal neurons born after injury develop abnormally and the number that survive long-term is debated. In experimental TBI, insulin-like growth factor-1 (IGF1) promotes hippocampal neuronal...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Cell Dev Biol
Main Authors: Littlejohn, Erica L., DeSana, Anthony J., Williams, Hannah C., Chapman, Rudy T., Joseph, Binoy, Juras, Jelena A., Saatman, Kathryn E.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Cell and Developmental Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174097/
https://ncbi.nlm.nih.gov/pubmed/34095131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.663456
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