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IGF1-Stimulated Posttraumatic Hippocampal Remodeling Is Not Dependent on mTOR

Adult hippocampal neurogenesis is stimulated acutely following traumatic brain injury (TBI). However, many hippocampal neurons born after injury develop abnormally and the number that survive long-term is debated. In experimental TBI, insulin-like growth factor-1 (IGF1) promotes hippocampal neuronal...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Littlejohn, Erica L., DeSana, Anthony J., Williams, Hannah C., Chapman, Rudy T., Joseph, Binoy, Juras, Jelena A., Saatman, Kathryn E.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174097/
https://ncbi.nlm.nih.gov/pubmed/34095131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.663456
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