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Insulin-like growth factor-1 overexpression increases long-term survival of posttrauma-born hippocampal neurons while inhibiting ectopic migration following traumatic brain injury

Cellular damage associated with traumatic brain injury (TBI) manifests in motor and cognitive dysfunction following injury. Experimental models of TBI reveal cell death in the granule cell layer (GCL) of the hippocampal dentate gyrus acutely after injury. Adult-born neurons residing in the neurogeni...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Littlejohn, Erica L., Scott, Danielle, Saatman, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7147070/
https://ncbi.nlm.nih.gov/pubmed/32276671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00925-6
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