Calpastatin Overexpression Protects against Excitotoxic Hippocampal Injury and Traumatic Spinal Cord Injury

Small molecule inhibitors of calcium-dependent proteases, calpains (CAPNs), protect against neurodegeneration induced by a variety of insults including excitotoxicity and spinal cord injury (SCI). Many of these compounds, however, also inhibit other proteases, which has made it difficult to evaluate...

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Pubblicato in:J Neurotrauma
Autori principali: Yu, Chen Guang, Bondada, Vimala, Joshi, Aashish, Reneer, Dexter V., Telling, Glenn C., Saatman, Kathryn E., Geddes, James W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7585603/
https://ncbi.nlm.nih.gov/pubmed/32718209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2020.7122
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