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Brain injury-induced proteolysis is reduced in a novel calpastatin overexpressing transgenic mouse
The calpain family of calcium-dependent proteases has been implicated in a variety of diseases and neurodegenerative pathologies. Prolonged activation of calpains results in proteolysis of numerous cellular substrates including cytoskeletal components and membrane receptors, contributing to cell dem...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676438/ https://ncbi.nlm.nih.gov/pubmed/23305291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12144 |
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