IGF1-Stimulated Posttraumatic Hippocampal Remodeling Is Not Dependent on mTOR

Adult hippocampal neurogenesis is stimulated acutely following traumatic brain injury (TBI). However, many hippocampal neurons born after injury develop abnormally and the number that survive long-term is debated. In experimental TBI, insulin-like growth factor-1 (IGF1) promotes hippocampal neuronal...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Littlejohn, Erica L., DeSana, Anthony J., Williams, Hannah C., Chapman, Rudy T., Joseph, Binoy, Juras, Jelena A., Saatman, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174097/
https://ncbi.nlm.nih.gov/pubmed/34095131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.663456
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