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Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt

Osteoclasts are giant bone cells formed by fusion from monocytes and uniquely capable of a complete destruction of mineralized tissues. Previously, we have demonstrated that in energy-rich environment not only osteoclast fusion index (the number of nuclei each osteoclast contains), but also cytoplas...

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Publicat a:Front Cell Dev Biol
Autors principals: Tiedemann, Kerstin, Le Nihouannen, Damien, Fong, Jenna E., Hussein, Osama, Barralet, Jake E., Komarova, Svetlana V.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435769/
https://ncbi.nlm.nih.gov/pubmed/28573133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00054
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