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The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner

The stimulatory effect of insulin on protein synthesis is due to its ability to activate various translation factors. We now show that insulin can increase protein synthesis capacity also by translational activation of TOP mRNAs encoding various components of the translation machinery. This translat...

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Detalhes bibliográficos
Main Authors: Patursky-Polischuk, Ilona, Stolovich-Rain, Miri, Hausner-Hanochi, Mirit, Kasir, Judith, Cybulski, Nadine, Avruch, Joseph, Rüegg, Markus A., Hall, Michael N., Meyuhas, Oded
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630691/
https://ncbi.nlm.nih.gov/pubmed/19047368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00980-08
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