Amino Acid-Induced Translation of TOP mRNAs Is Fully Dependent on Phosphatidylinositol 3-Kinase-Mediated Signaling, Is Partially Inhibited by Rapamycin, and Is Independent of S6K1 and rpS6 Phosphorylation

Vertebrate TOP mRNAs contain an oligopyrimidine tract at their 5′ termini (5′TOP) and encode components of the translational machinery. Previously it has been shown that they are subject to selective translational repression upon growth arrest and that their translational behavior correlates with th...

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Detalhes bibliográficos
Main Authors: Tang, Hua, Hornstein, Eran, Stolovich, Miri, Levy, Galit, Livingstone, Mark, Templeton, Dennis, Avruch, Joseph, Meyuhas, Oded
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100027/
https://ncbi.nlm.nih.gov/pubmed/11713299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8671-8683.2001
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