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A Genome-wide RNAi Screen for Polypeptides that Alter rpS6 Phosphorylation
Mammalian target of rapamycin (mTOR) is a giant protein kinase that controls cell proliferation, growth, and metabolism. mTOR is regulated by nutrient availability, by mitogens, and by stress, and operates through two independently regulated hetero-oligomeric complexes. We have attempted to identify...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535007/ https://ncbi.nlm.nih.gov/pubmed/22125066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-430-8_11 |
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