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Early changes in rpS6 phosphorylation and BH3 profiling predict response to chemotherapy in AML cells

Blasts from different patients with acute myeloid leukemia (AML) vary in the agent(s) to which they are most responsive. With a myriad of novel agents to evaluate, there is a lack of predictive biomarkers to precisely assign targeted therapies to individual patients. Primary AML cells often survive...

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Publicat a:PLoS One
Autors principals: Grundy, Martin, Jones, Thomas, Elmi, Liban, Hall, Michael, Graham, Adam, Russell, Nigel, Pallis, Monica
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933738/
https://ncbi.nlm.nih.gov/pubmed/29723246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196805
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