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Early changes in rpS6 phosphorylation and BH3 profiling predict response to chemotherapy in AML cells

Blasts from different patients with acute myeloid leukemia (AML) vary in the agent(s) to which they are most responsive. With a myriad of novel agents to evaluate, there is a lack of predictive biomarkers to precisely assign targeted therapies to individual patients. Primary AML cells often survive...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Grundy, Martin, Jones, Thomas, Elmi, Liban, Hall, Michael, Graham, Adam, Russell, Nigel, Pallis, Monica
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933738/
https://ncbi.nlm.nih.gov/pubmed/29723246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196805
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