Reassessment of the Role of TSC, mTORC1 and MicroRNAs in Amino Acids-Meditated Translational Control of TOP mRNAs

TOP mRNAs encode components of the translational apparatus, and repression of their translation comprises one mechanism, by which cells encountering amino acid deprivation downregulate the biosynthesis of the protein synthesis machinery. This mode of regulation involves TSC as knockout of TSC1 or TS...

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Detalhes bibliográficos
Main Authors: Patursky-Polischuk, Ilona, Kasir, Judith, Miloslavski, Rachel, Hayouka, Zvi, Hausner-Hanochi, Mirit, Stolovich-Rain, Miri, Tsukerman, Pinchas, Biton, Moshe, Mudhasani, Rajini, Jones, Stephen N., Meyuhas, Oded
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206288/
https://ncbi.nlm.nih.gov/pubmed/25338081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109410
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