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Moderate excess of pyruvate augments osteoclastogenesis

Cell differentiation leads to adaptive changes in energy metabolism. Conversely, hyperglycemia induces malfunction of many body systems, including bone, suggesting that energy metabolism reciprocally affects cell differentiation. We investigated how the differentiation of bone-resorbing osteoclasts,...

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Detalhes bibliográficos
Main Authors: Fong, Jenna E., Le Nihouannen, Damien, Tiedemann, Kerstin, Sadvakassova, Gulzhakhan, Barralet, Jake E., Komarova, Svetlana V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625867/
https://ncbi.nlm.nih.gov/pubmed/23616923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20133269
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