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Moderate excess of pyruvate augments osteoclastogenesis

Cell differentiation leads to adaptive changes in energy metabolism. Conversely, hyperglycemia induces malfunction of many body systems, including bone, suggesting that energy metabolism reciprocally affects cell differentiation. We investigated how the differentiation of bone-resorbing osteoclasts,...

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Autores principales: Fong, Jenna E., Le Nihouannen, Damien, Tiedemann, Kerstin, Sadvakassova, Gulzhakhan, Barralet, Jake E., Komarova, Svetlana V.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625867/
https://ncbi.nlm.nih.gov/pubmed/23616923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20133269
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