Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis()

Bone metastasis from breast and prostate carcinomas is facilitated by activation of bone-resorbing osteoclasts. Using proteomics approaches, we have identified peroxiredoxin-4 (PRDX4) as a cancer-secreted mediator of osteoclastogenesis. We now report characterization of L-plastin in the conditioned...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Tiedemann, Kerstin, Sadvakassova, Gulzhakhan, Mikolajewicz, Nicholas, Juhas, Michal, Sabirova, Zarina, Tabariès, Sébastien, Gettemans, Jan, Siegel, Peter M., Komarova, Svetlana V.
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2018
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Original article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305809/
https://ncbi.nlm.nih.gov/pubmed/30583289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.11.014
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