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Active hematopoiesis triggers exosomal release of PRDX2 that promotes osteoclast formation

Hematopoietic disorders, particularly hemolytic anemias, commonly lead to bone loss. We have previously reported that actively proliferating cancer cells stimulate osteoclastogenesis from late precursors in a RANKL‐independent manner. We theorized that cancer cells exploit the physiological role of...

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Bibliografische gegevens
Gepubliceerd in:Physiol Rep
Hoofdauteurs: Sadvakassova, Gulzhakhan, Tiedemann, Kerstin, Steer, Kieran J. D., Mikolajewicz, Nicholas, Stavnichuk, Mariya, In‐Kyung Lee, Irene, Sabirova, Zarina, Schranzhofer, Matthias, Komarova, Svetlana V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883842/
https://ncbi.nlm.nih.gov/pubmed/33587325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14745
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