Moderate excess of pyruvate augments osteoclastogenesis

Cell differentiation leads to adaptive changes in energy metabolism. Conversely, hyperglycemia induces malfunction of many body systems, including bone, suggesting that energy metabolism reciprocally affects cell differentiation. We investigated how the differentiation of bone-resorbing osteoclasts,...

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Main Authors: Fong, Jenna E., Le Nihouannen, Damien, Tiedemann, Kerstin, Sadvakassova, Gulzhakhan, Barralet, Jake E., Komarova, Svetlana V.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625867/
https://ncbi.nlm.nih.gov/pubmed/23616923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20133269
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