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SARM1 is required in human derived sensory neurons for injury-induced and neurotoxic axon degeneration
Axonal degeneration contributes to the pathogenesis of many neurodegenerative disorders, motivating efforts to dissect the mechanism of pathological axon loss in order to develop therapies for axonal preservation. SARM1 is a particularly attractive therapeutic target, as it is an inducible NAD(+) cl...
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| 出版年: | Exp Neurol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8171232/ https://ncbi.nlm.nih.gov/pubmed/33548217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2021.113636 |
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