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Mitochondrial Dysfunction Induces Sarm1-Dependent Cell Death in Sensory Neurons

Mitochondrial dysfunction is the underlying cause of many neurological disorders, including peripheral neuropathies. Mitochondria rely on a proton gradient to generate ATP and interfering with electron transport chain function can lead to the deleterious accumulation of reactive oxygen species (ROS)...

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Detalhes bibliográficos
Main Authors: Summers, Daniel W., DiAntonio, Aaron, Milbrandt, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087211/
https://ncbi.nlm.nih.gov/pubmed/25009267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0877-14.2014
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