The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13

Dendritic cells (DCs) are indispensable for defense against pathogens but may also contribute to immunopathology. Activation of DCs upon the sensing of pathogens by Toll-like receptors (TLRs) is largely mediated by pattern recognition receptor/nuclear factor-κB (NF-κB) signaling and depends on the a...

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Detaylı Bibliyografya
Yayımlandı:Cell Mol Immunol
Asıl Yazarlar: Mulas, Floriana, Wang, Xu, Song, Shanshan, Nishanth, Gopala, Yi, Wenjing, Brunn, Anna, Larsen, Pia-Katharina, Isermann, Berend, Kalinke, Ulrich, Barragan, Antonio, Naumann, Michael, Deckert, Martina, Schlüter, Dirk
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167118/
https://ncbi.nlm.nih.gov/pubmed/32024978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-0362-6
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