The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13

Dendritic cells (DCs) are indispensable for defense against pathogens but may also contribute to immunopathology. Activation of DCs upon the sensing of pathogens by Toll-like receptors (TLRs) is largely mediated by pattern recognition receptor/nuclear factor-κB (NF-κB) signaling and depends on the a...

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Publicado no:Cell Mol Immunol
Main Authors: Mulas, Floriana, Wang, Xu, Song, Shanshan, Nishanth, Gopala, Yi, Wenjing, Brunn, Anna, Larsen, Pia-Katharina, Isermann, Berend, Kalinke, Ulrich, Barragan, Antonio, Naumann, Michael, Deckert, Martina, Schlüter, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167118/
https://ncbi.nlm.nih.gov/pubmed/32024978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-0362-6
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