OTUB1 inhibits CNS autoimmunity by preventing IFN‐γ‐induced hyperactivation of astrocytes

Astrocytes are critical regulators of neuroinflammation in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). Growing evidence indicates that ubiquitination of signaling molecules is an important cell‐intrinsic mechanism governing astrocyte function during...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Wang, Xu, Mulas, Floriana, Yi, Wenjing, Brunn, Anna, Nishanth, Gopala, Just, Sissy, Waisman, Ari, Brück, Wolfgang, Deckert, Martina, Schlüter, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517825/
https://ncbi.nlm.nih.gov/pubmed/30944096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100947
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