OTUB1 inhibits CNS autoimmunity by preventing IFN‐γ‐induced hyperactivation of astrocytes

Astrocytes are critical regulators of neuroinflammation in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). Growing evidence indicates that ubiquitination of signaling molecules is an important cell‐intrinsic mechanism governing astrocyte function during...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Wang, Xu, Mulas, Floriana, Yi, Wenjing, Brunn, Anna, Nishanth, Gopala, Just, Sissy, Waisman, Ari, Brück, Wolfgang, Deckert, Martina, Schlüter, Dirk
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517825/
https://ncbi.nlm.nih.gov/pubmed/30944096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100947
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