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OTUB1 inhibits CNS autoimmunity by preventing IFN‐γ‐induced hyperactivation of astrocytes

Astrocytes are critical regulators of neuroinflammation in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). Growing evidence indicates that ubiquitination of signaling molecules is an important cell‐intrinsic mechanism governing astrocyte function during...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Wang, Xu, Mulas, Floriana, Yi, Wenjing, Brunn, Anna, Nishanth, Gopala, Just, Sissy, Waisman, Ari, Brück, Wolfgang, Deckert, Martina, Schlüter, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517825/
https://ncbi.nlm.nih.gov/pubmed/30944096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100947
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