טוען...
Molecular Modelling Guided Design, Synthesis and QSAR Analysis of New Small Molecule Non-Lipid Autotaxin Inhibitors
The lysophospholipase D autotaxin (ATX) generates lysophosphatidic acid (LPA) that activates six cognate G-protein coupled receptors (GPCR) in cancerous cells, promoting their motility and invasion. Four novel compounds were generated aided by molecular docking guided design and synthesis techniques...
שמור ב:
| הוצא לאור ב: | Bioorg Chem |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8163515/ https://ncbi.nlm.nih.gov/pubmed/32890995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2020.104188 |
| תגים: |
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