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Temperature-Dependent Reactivity of a Non-heme Fe(III)(OH)(SR) Complex: Relevance to Isopenicillin N Synthase

Non-heme iron complexes with cis-Fe(III)(OH)(SAr/OAr) coordination were isolated and examined for their reactivity with a tertiary carbon radical. The sulfur-ligated complex shows a temperature dependence on ·OH versus ArS transfer, whereas the oxygen-ligated complex does not. These results provide...

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Foilsithe in:J Am Chem Soc
Main Authors: Yadav, Vishal, Siegler, Maxime A., Goldberg, David P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130865/
https://ncbi.nlm.nih.gov/pubmed/33356198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09688
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