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Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion
Metabolic fuels regulate insulin secretion by generating second messengers that drive insulin granule exocytosis, but the biochemical pathways involved are incompletely understood. Here we demonstrate that stimulation of rat insulinoma cells or primary rat islets with glucose or glutamine + 2-aminob...
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| Publicado no: | Cell Metab |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8115731/ https://ncbi.nlm.nih.gov/pubmed/33321098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.11.020 |
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