Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion

Metabolic fuels regulate insulin secretion by generating second messengers that drive insulin granule exocytosis, but the biochemical pathways involved are incompletely understood. Here we demonstrate that stimulation of rat insulinoma cells or primary rat islets with glucose or glutamine + 2-aminob...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Metab
Egile Nagusiak: Zhang, Guo-Fang, Jensen, Mette V., Gray, Sarah M., El, Kimberley, Wang, You, Lu, Danhong, Becker, Thomas C., Campbell, Jonathan E., Newgard, Christopher B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115731/
https://ncbi.nlm.nih.gov/pubmed/33321098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.11.020
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