Metabolic cycling in control of glucose-stimulated insulin secretion

Glucose-stimulated insulin secretion (GSIS) is central to normal control of metabolic fuel homeostasis, and its impairment is a key element of β-cell failure in type 2 diabetes. Glucose exerts its effects on insulin secretion via its metabolism in β-cells to generate stimulus/secretion coupling fact...

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Main Authors: Jensen, Mette V., Joseph, Jamie W., Ronnebaum, Sarah M., Burgess, Shawn C., Sherry, A. Dean, Newgard, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603555/
https://ncbi.nlm.nih.gov/pubmed/18728221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90604.2008
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