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Metabolic cycling in control of glucose-stimulated insulin secretion
Glucose-stimulated insulin secretion (GSIS) is central to normal control of metabolic fuel homeostasis, and its impairment is a key element of β-cell failure in type 2 diabetes. Glucose exerts its effects on insulin secretion via its metabolism in β-cells to generate stimulus/secretion coupling fact...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2603555/ https://ncbi.nlm.nih.gov/pubmed/18728221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90604.2008 |
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