(13)C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

Cellular metabolism of glucose is required for stimulation of insulin secretion from pancreatic β cells, but the precise metabolic coupling factors involved in this process are not known. In an effort to better understand mechanisms of fuel-mediated insulin secretion, we have adapted (13)C NMR and i...

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Autori principali: Lu, Danhong, Mulder, Hindrik, Zhao, Piyu, Burgess, Shawn C., Jensen, Mette V., Kamzolova, Svetlana, Newgard, Christopher B., Sherry, A. Dean
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122412/
https://ncbi.nlm.nih.gov/pubmed/11880625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052005699
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