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Propionate stimulates pyruvate oxidation in the presence of acetate

Flux through pyruvate dehydrogenase (PDH) in the heart may be reduced by various forms of injury to the myocardium, or by oxidation of alternative substrates in normal heart tissue. It is important to distinguish these two mechanisms because imaging of flux through PDH based on the appearance of hyp...

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Detalhes bibliográficos
Main Authors: Purmal, Colin, Kucejova, Blanka, Sherry, A. Dean, Burgess, Shawn C., Malloy, Craig. R., Merritt, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200343/
https://ncbi.nlm.nih.gov/pubmed/25320331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00407.2014
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